Surface optimization of gold nanoparticle mass tags for the sensitive detection of protein biomarkers via immuno-capture LI-MS-Reference-Cited by-同舟云学术

Surface optimization of gold nanoparticle mass tags for the sensitive detection of protein biomarkers via immuno-capture LI-MS

Published:2020 Issue:19 Volume:145 Page:6237-6242
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Tam Toby Siu-Chung¹²³⁴,Cheng Yu-Hong¹²³⁴^ORCID,Lok Chun-Nam¹²³⁴^ORCID,Au-Yeung Ho Yu¹²³⁴^ORCID,Ni Wen-Xiu⁵⁶⁴,Wei Xiao-Long⁷⁸⁶⁴,Ng Kwan-Ming¹²³⁴⁹^ORCID

Affiliation:

1. Department of Chemistry and State Key Laboratory of Synthetic Chemistry

2. The University of Hong Kong

3. Hong Kong S.A.R.

4. P. R. China

5. Shantou University Medical College

6. Guangdong

7. Department of Pathology

8. The Cancer Hospital of Shantou University Medical College

9. Department of Chemistry and Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province

Abstract

Optimal surface functionalization of antibody-conjugated AuNPs for modulating specific versus non-specific interactions to enhance protein detection sensitivity.

Funder

University of Hong Kong

Shantou University

Li Ka Shing Foundation

Research Grants Council, University Grants Committee

University Grants Committee

Universidade de Macau

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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