Device for whole genome sequencing single circulating tumor cells from whole blood-Reference-Cited by-同舟云学术

Device for whole genome sequencing single circulating tumor cells from whole blood

Published:2019 Issue:19 Volume:19 Page:3168-3178
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Li Ren¹²³⁴⁵^ORCID,Jia Fei¹²³⁴⁵^ORCID,Zhang Weikai⁶⁷⁸⁹¹⁰,Shi Fanghao¹²³⁴⁵,Fang Zhiguo¹²³⁴⁵,Zhao Hong¹¹¹²¹³¹⁴¹⁵,Hu Zhiyuan¹²³⁴⁵,Wei Zewen⁶⁷⁸⁹¹⁰

Affiliation:

1. CAS Key Laboratory of Standardization and Measurement for Nanotechnology

2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety

3. CAS Center for Excellence in Nanoscience

4. National Center for Nanoscience and Technology of China

5. Beijing 100190

6. Department of Biomedical Engineering

7. School of Life Science

8. Beijing Institute of Technology

9. Beijing

10. P. R. China

11. Department of Hepatobiliary Surgery and Department of Pathology

12. State Key Laboratory of Molecular Oncology

13. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital

14. Chinese Academy of Medical Sciences and Peking Union Medical College

15. Beijing 100021

Abstract

To sequence single circulating tumor cells (CTCs) from whole blood, a microfluidic chip was developed to perform blood filtering/CTC enrichment/CTC sorting and in situ MDA for whole genome sequencing.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Natural Science Foundation of Beijing Municipality

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00473D

Reference29 articles.

1. Circulating and disseminated tumour cells — mechanisms of immune surveillance and escape

2. Isolation of rare circulating tumour cells in cancer patients by microchip technology

3. Size-selective collection of circulating tumor cells using Vortex technology

4. Association of Circulating Tumor Cells With Late Recurrence of Estrogen Receptor–Positive Breast Cancer

5. Circulating Tumor Cells as Biomarkers in Prostate Cancer

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