Photothermal-responsive Prussian blue nanocages loaded with thrombin for tumor starvation therapy and photothermal therapy

Author:

Liu Yang1,Yue Bingjie1,Wang Ranran2ORCID,Cong Hailin134ORCID,Hu Hao1ORCID,Yu Bing14ORCID,Shen Youqing15

Affiliation:

1. College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China

2. Institute of Rehabilitation Medicine, School of Rehabilitation Medicine, Binzhou Medical University, Yantai, 264003, PR China

3. School of Materials Science and Engineering, Shandong University of Technology, Zibo 255000, China

4. State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao, 266071, China

5. Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Center for Bionanoengineering, and Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China

Abstract

The goal of inhibiting tumor growth can be achieved by cutting off the supply of nutrients in the blood vessels of a tumor site, but finding ways to effectively, accurately and safely deliver drugs that can induce vascular embolism remains a challenge.

Funder

Natural Science Foundation of Shandong Province

Qingdao Municipal Science and Technology Bureau

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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