Recent advances in stimuli-responsive polymeric carriers for controllable CRISPR/Cas9 gene editing system delivery-Reference-Cited by-同舟云学术

Recent advances in stimuli-responsive polymeric carriers for controllable CRISPR/Cas9 gene editing system delivery

Published:2023 Issue:15 Volume:11 Page:5078-5094
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Ma Panqin¹,Wang Qi¹,Luo Xi²,Mao Liuzhou¹,Wang Zhanxiang²,Ye Enyi³⁴^ORCID,Loh Xian Jun³⁴^ORCID,Li Zibiao³⁴⁵^ORCID,Wu Yun-Long¹^ORCID

Affiliation:

1. Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, China

2. BE/Phase I Clinical Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361000, China

3. Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03, Singapore 138634, Singapore

4. Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), A*STAR, 1 Pesek Road, Jurong Island, 627833, Singapore

5. Department of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, 117576, Singapore

Abstract

Stimulus-responsive polymer delivery vectors with modifiable architectures can load and deliver CRISPR gene editing systems in a controlled manner, which improves the effectiveness of gene editing towards potential clinical disease treatment.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Science and Engineering Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00529A

Reference105 articles.

1. Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing