One-step prepared nano-in-micro microcapsule delivery vehicle with sequential burst–sustained drug release for the targeted treatment of inflammatory bowel disease-Reference-Cited by-同舟云学术

One-step prepared nano-in-micro microcapsule delivery vehicle with sequential burst–sustained drug release for the targeted treatment of inflammatory bowel disease

Published:2021 Issue:16 Volume:5 Page:6027-6040
ISSN:2052-1537
Container-title:Materials Chemistry Frontiers
language:en
Short-container-title:Mater. Chem. Front.

Author:

Jiang Jingjing¹²³⁴,Xiao Jingcheng¹²³⁴,Zhao Zexu¹²³⁴,Yuan Mao-Sen¹²³⁴^ORCID,Wang Jinyi¹²³⁴^ORCID

Affiliation:

1. College of Chemistry & Pharmacy

2. Northwest A&F University

3. Yangling

4. China

Abstract

A smart microcapsule for targeted therapy of IBD is prepared through droplet microfluidics. It can achieve sequential burst–sustained drug release, which is appropriate for the treatment of IBD from the point of view of pharmacology and pathology.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QM/D1QM00589H

Reference47 articles.

1. Nanomedicine and drug delivery strategies for treatment of inflammatory bowel disease

2. Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: Selective targeting to diseased versus healthy tissue

3. Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases