Vulgarisin-type diterpenoids from self-heal (Prunella vulgaris) and their neuroprotective effects against ischemia/reperfusion (I/R) via a mitochondria-related pathway

Author:

Ma Fengwei1234ORCID,Deng Qingfang15,Lou Huayong23,Li Jinyu23,Xu Su4,Wu Wenneng4,Wen Qihua4,Tang Lei2,Wang Xin1,Pan Weidong23

Affiliation:

1. State Key Laboratory of Cellular Stress Biology, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361005, China

2. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China

3. The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Science, Guiyang 550014, China

4. Food and Pharmaceutical Engineering Institute, Guiyang University, Guiyang, Guizhou, 550005, China

5. Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guiyang Normal University, Guiyang, Guizhou, 550001, China

Abstract

Twelve vulgarisin-type diterpenoids were obtained from self-heal. Their absolute configurations were elucidated. These vulgarisin-type diterpenoids possess neuroprotective effects.

Funder

State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University

National Natural Science Foundation of China

Guizhou Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3