A generator of peroxynitrite activatable with red light-Reference-Cited by-同舟云学术

A generator of peroxynitrite activatable with red light

Published:2021 Issue:13 Volume:12 Page:4740-4746
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Parisi Cristina¹²³⁴^ORCID,Failla Mariacristina⁵⁶⁷⁴^ORCID,Fraix Aurore¹²³⁴^ORCID,Menilli Luca⁸⁹¹⁰⁴^ORCID,Moret Francesca⁸⁹¹⁰⁴^ORCID,Reddi Elena⁸⁹¹⁰⁴^ORCID,Rolando Barbara⁵⁶⁷⁴,Spyrakis Francesca⁵⁶⁷⁴,Lazzarato Loretta⁵⁶⁷⁴^ORCID,Fruttero Roberta⁵⁶⁷⁴,Gasco Alberto⁵⁶⁷⁴,Sortino Salvatore¹²³⁴^ORCID

Affiliation:

1. PhotoChemLab

2. Department of Drug and Health Sciences

3. University of Catania

4. Italy

5. Department of Science and Drug Technology

6. University of Torino

7. I-10125 Torino

8. Department of Biology

9. University of Padova

10. I-35131 Padova

Abstract

Excitation of a molecular hybrid with highly biocompatible red light generates cytotoxic peroxynitrite, produces red fluorescence useful for cell tracking and induces remarkable cancer cell death at very low concentrations and very low light doses.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC06970A

Reference54 articles.

1. Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution

2. Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pressure Stopped-Flow Technique, and Pulse Radiolysis

3. The reaction of NO· with O2·− and HO2·−: A pulse radiolysis study