Interaction of polyelectrolyte-shell cubosomes with serum albumin for triggering drug release in gastrointestinal cancer

Author:

Pimenta Barbara V.1,Madrid Rafael R.M.1,Mathews Patrick D.1,Riske Karin A.1,Loh Watson2,Angelov Borislav3,Angelova Angelina4,Mertins Omar14ORCID

Affiliation:

1. Laboratory of Nano Bio Materials (LNBM), Department of Biophysics, Paulista Medical School, Federal University of Sao Paulo (UNIFESP), 04023-062 Sao Paulo, Brazil

2. Institute of Chemistry, State University of Campinas (UNICAMP), 13083-970 Campinas, Brazil

3. Institute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, CZ-18221 Prague, Czech Republic

4. Université Paris-Saclay, CNRS, Institut Galien Paris-Saclay, 91400 Orsay, France

Abstract

Biopolymers-tailored cubosomes in contact with albumin endure phase change leading to release of encapsulated content which may provide effective drug release in digestive cancer treatments.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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