Novel quinoxaline-3-propanamides as VGFR-2 inhibitors and apoptosis inducers-Reference-Cited by-同舟云学术

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Novel quinoxaline-3-propanamides as VGFR-2 inhibitors and apoptosis inducers

Published:2023 Issue:45 Volume:13 Page:31908-31924
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ismail Magda M. F.¹^ORCID,Shawer Taghreed Z.¹,Ibrahim Rabab S.¹,Abusaif Mostafa S.²,Kamal Mona M.³,Allam Rasha M.⁴,Ammar Yousry A.²

Affiliation:

1. Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, 11754, Egypt

2. Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, 11754, Egypt

3. Department of Pharmacology, Faculty of Pharmacy (Girls), 11754 Al-Azhar University, Cairo, Egypt

4. Department of Pharmacology, Medical and Clinical Research Institute, National Research Centre, 12622, Dokki, Cairo, Egypt

Abstract

Vascular endothelial growth factor receptor-2 is a vital target for therapeutic mediation in various types of cancer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA05066A

Reference52 articles.

1. New insights into the role of co-receptor neuropilins in tumour angiogenesis and lymphangiogenesis and targeted therapy strategies

2. VEGFa/VEGFR2 autocrine and paracrine signaling promotes cervical carcinogenesis via β-catenin and snail

3. Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

4. Therapeutic Inhibition of VEGF Signaling and Associated Nephrotoxicities

5. The role and significance of VEGFR2⁺ regulatory T cells in tumor immunity

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