Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway-Reference-Cited by-同舟云学术

Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway

Published:2021 Issue:17 Volume:12 Page:8056-8067
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Xian Minghua¹²³^ORCID,Cai Jiale¹²³,Zheng Kening¹²³,Liu Qu¹²³,Liu Yali¹²³,Lin Huiting¹²³,Liang Shengwang¹²³,Wang Shumei²³⁴

Affiliation:

1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China

2. Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, Guangzhou 510006, China

3. Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, Guangzhou 510006, China

4. School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China

Abstract

Study of the protective role of aloe-emodin in nerve injury and neuroinflammation in vivo and in vitro, to provide a scientific basis for aloe-emodin treatment of neurological diseases.

Funder

State Administration of Traditional Chinese Medicine of the People's Republic of China

National Natural Science Foundation of China

Guangzhou Municipal Science and Technology Project

National Major Science and Technology Projects of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO01144H

Reference41 articles.

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3. Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury

4. Icariside II attenuates cerebral ischemia/reperfusion-induced blood–brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1

5. Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti‐Neuroinflammatory Agents for Ischemic Stroke

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