Overcoming barriers in non-viral gene delivery for neurological applications

Author:

Tasset Aaron1,Bellamkonda Arjun1ORCID,Wang Wenliang1,Pyatnitskiy Ilya1ORCID,Ward Deidra1ORCID,Peppas Nicholas12345ORCID,Wang Huiliang1ORCID

Affiliation:

1. Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA

2. Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA

3. Institute for Biomaterials, Drug Delivery, and Regenerative Medicine, The University of Texas at Austin, Austin, TX, USA

4. Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX, USA

5. Department of Surgery and Perioperative Care, Dell Medical School, The University of Texas at Austin, Austin, TX, USA

Abstract

Investigation of various strategies to overcome extracellular and intracellular barriers for improved gene delivery in neuronal applications utilizing non-viral vectors.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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