Evaluation of focused beam reflectance measurement (FBRM) for monitoring and predicting the crystal size of carbamazepine in crystallization processes-Reference-Cited by-同舟云学术

Evaluation of focused beam reflectance measurement (FBRM) for monitoring and predicting the crystal size of carbamazepine in crystallization processes

Published:2021 Issue:4 Volume:23 Page:972-985
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Acevedo David¹²³⁴⁵^ORCID,Wu Wei-Lee¹²³⁴⁵,Yang Xiaochuan¹²³⁴⁵^ORCID,Pavurala Naresh¹²³⁴⁵,Mohammad Adil¹²³⁴⁵^ORCID,O'Connor Thomas F.¹²³⁴⁵

Affiliation:

1. Office of Pharmaceutical Quality

2. CDER

3. FDA

4. Silver Spring

5. USA

Abstract

Pharmaceutical crystallization affects the properties of APIs as it determines the purity and crystal size distribution, among other attributes. This work presents two CLD–CSD models, theoretical and empirical, for a model compound.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CE/D0CE01388A

Reference58 articles.

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