Modulating chitin synthesis in marine algae with iminosugars obtained by SmI<sub>2</sub> and FeCl<sub>3</sub>-mediated diastereoselective carbonyl ene reaction-Reference-Cited by-同舟云学术

Modulating chitin synthesis in marine algae with iminosugars obtained by SmI₂ and FeCl₃-mediated diastereoselective carbonyl ene reaction

Published:2022 Issue:33 Volume:20 Page:6606-6618
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Holzwarth Marcel¹,Ludwig Jan²^ORCID,Bernz Alexander¹,Claasen Birgit¹,Majoul Asma²,Reuter Julia²,Zens Anna¹,Pawletta Brigitte³,Bilitewski Ursula³,Weiss Ingrid M.²⁴⁵^ORCID,Laschat Sabine¹^ORCID

Affiliation:

1. Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569 Stuttgart, Germany

2. Institut für Biomaterialien und Biomolekulare Systeme, Universität Stuttgart, Pfaffenwaldring 57, D-70569 Stuttgart, Germany

3. Abteilung Chemische Biologie, Helmholtz-Zentrum für Infektionsforschung, Inhoffenstr. 7, D-38124 Braunschweig, Germany

4. AMICA – Stuttgart Research Focus (SRF), University of Stuttgart, Pfaffenwaldring 32, 70569 Stuttgart, Germany

5. Suttgart Research Center Systems Biology (SRCSB), University of Stuttgart, Stuttgart 70569, Germany

Abstract

Samarium iodide was employed in a stereoselective cyclization, starting from enantiopure amino acids towards iminosugar analogues, which influence chitin synthesis in the eukaryotic algae Thalassiosira as quantified in vivo via light microscopy.

Funder

European Regional Development Fund

Carl-Zeiss-Stiftung

Deutsche Forschungsgemeinschaft

Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00907B

Reference82 articles.