Natural alkaloids from lotus plumule ameliorate lipopolysaccharide-induced depression-like behavior: integrating network pharmacology and molecular mechanism evaluation-Reference-Cited by-同舟云学术

Natural alkaloids from lotus plumule ameliorate lipopolysaccharide-induced depression-like behavior: integrating network pharmacology and molecular mechanism evaluation

Published:2019 Issue:9 Volume:10 Page:6062-6073
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chen Sixuan¹²³⁴⁵,Guo Wanyi¹²³⁴⁵,Qi Xiaoxiao¹²³⁴⁵,Zhou Jiuyao¹²³⁴⁵,Liu Zhongqiu¹²³⁴⁵,Cheng Yuanyuan¹²³⁴⁵^ORCID

Affiliation:

1. Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China

2. International Institute for Translational Chinese Medicine

3. School of Pharmaceutical Sciences

4. Guangzhou University Chinese Medicine

5. Guangzhou

Abstract

Alkaloids from lotus plumule regulated BDNF-mediated ER stress and autophagy, subsequently attenuating neuroinflammation in LPS-stimulated BV2 microglia and LPS-induced depressive C56BL/6N mice.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO01092K

Reference36 articles.

1. Antidepressant adherence patterns in older patients: use of a clustering method on a prescription database

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