Application of the UHPLC method for separation and characterization of major photolytic degradation products of trazodone by LC-MS and NMR
Author:
Affiliation:
1. Department of Pharmaceutical Analysis
2. National Institute of Pharmaceutical Education and Research (NIPER)
3. Balanagar
4. Hyderabad
5. India
Abstract
This article is about the characterization of degradation products of trazodone which is used in the treatment of depression.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ03545H
Reference25 articles.
1. A comparison of trazodone and fluoxetine: implications for a serotonergic mechanis of antidepressant action
2. Anxiety and Depression
3. Rediscovering Trazodone for the Treatment of Major Depressive Disorder
4. FDA Approved Drug Products, available from: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm
5. Forced degradation studies to assess the stability of drugs and products
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