Microenvironmental influence on microtumour infiltration patterns: 3D-mathematical modelling supported byin vitrostudies-Reference-Cited by-同舟云学术

Microenvironmental influence on microtumour infiltration patterns: 3D-mathematical modelling supported byin vitrostudies

Published:2018 Issue:5 Volume:10 Page:325-334
ISSN:1757-9694
Container-title:Integrative Biology
language:en
Short-container-title:Integr. Biol.

Author:

Luján Emmanuel¹²³⁴⁵,Soto Daniela⁶⁷⁸⁴⁵,Rosito María S.⁹³⁴⁵,Soba Alejandro¹⁰¹¹⁴⁵,Guerra Liliana N.⁶⁷⁸⁴⁵,Calvo Juan C.⁶⁷⁸⁴⁵^ORCID,Marshall Guillermo¹²³⁴⁵^ORCID,Suárez Cecilia¹²³⁴⁵^ORCID

Affiliation:

1. Laboratorio de Sistemas Complejos

2. Instituto de Física del Plasma

3. CONICET-UBA

4. Buenos Aires

5. Argentina

6. Departamento de Química Biológica

7. Facultad de Ciencias Exactas y Naturales

8. UBA

9. Instituto de Astronomía y Física del Espacio

10. Comisión Nacional de Energía Atómica

11. CONICET

Abstract

We present a new mathematical model with the ability to describe the growth and infiltration patterns of multicellular tumour spheroids immersed under different microenvironmental conditions.

Funder

Universidad de Buenos Aires

Consejo Nacional de Investigaciones Científicas y Técnicas

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2018/IB/C8IB00049B

Reference51 articles.

1. Role of Microenvironment in Glioma Invasion: What We Learned from In Vitro Models

2. In Vitro Microtumors Provide a Physiologically Predictive Tool for Breast Cancer Therapeutic Screening

3. Three-dimensional culture systems in cancer research: Focus on tumor spheroid model

4. The effect of fibrillar matrix architecture on tumor cell invasion of physically challenging environments

5. Recapitulating epithelial tumor microenvironment in vitro using three dimensional tri-culture of human epithelial, endothelial, and mesenchymal cells

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