Synthesis and antimicrobial evaluation of promising 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and their halogenated amino compounds for treating Gram-negative bacterial infections-Reference-Cited by-同舟云学术

Synthesis and antimicrobial evaluation of promising 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and their halogenated amino compounds for treating Gram-negative bacterial infections

Published:2017 Issue:30 Volume:7 Page:18311-18320
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Novais Juliana S.¹²³⁴,Campos Vinicius R.²⁵⁶⁷⁴,Silva Ana Carolina J. A.¹²³⁴,de Souza Maria C. B. V.²⁵⁶⁷⁴,Ferreira Vitor F.²⁵⁶⁷⁴,Keller Vitor G. L.²⁵⁶⁷⁴,Ferreira Matheus O.²⁵⁶⁷⁴,Dias Flaviana R. F.²⁵⁶⁷⁴,Vitorino Maíra I.¹²³⁴,Sathler Plínio C.⁸⁹¹⁰¹¹⁴,Santana Marcos V.¹²³⁴,Resende Jackson A. L. C.²¹²⁶³⁴,Castro Helena C.¹²³⁴,Cunha Anna C.²⁵⁶⁷⁴^ORCID

Affiliation:

1. Programa de Pós-Graduação em Ciências e Biotecnologia

2. Universidade Federal Fluminense

3. Niterói

4. Brazil

5. Departamento de Química Orgânica

6. Programa de Pós-Graduação em Química

7. 24020-141 Niterói

8. Universidade Federal do Rio de Janeiro

9. Faculdade de Farmácia

10. LabTIF

11. Rio de Janeiro

12. Laboratório de difração de raios X

Abstract

In this work we described the synthesis and antimicrobial evaluation of 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates derivatives that exhibited remarkable activity against two Gram-negative strains of clinical importance.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA00825B

Reference64 articles.

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