Shuttle/sink model composed of β-cyclodextrin and simvastatin-loaded discoidal reconstituted high-density lipoprotein for enhanced cholesterol efflux and drug uptake in macrophage/foam cells-Reference-Cited by-同舟云学术

Shuttle/sink model composed of β-cyclodextrin and simvastatin-loaded discoidal reconstituted high-density lipoprotein for enhanced cholesterol efflux and drug uptake in macrophage/foam cells

Published:2020 Issue:7 Volume:8 Page:1496-1506
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

He Jianhua¹²³⁴,Yang Yun¹²³⁴⁵,Zhou Xiaoju¹²³⁴⁶,Zhang Wenli¹²³⁴,Liu Jianping¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutics

2. China Pharmaceutical University

3. Nanjing

4. P. R. China

5. State Key Laboratory of Long-acting and Targeting Drug Delivery System

6. Institute of Pharmaceutics

Abstract

The combination of β-CD and ST-d-rHDL could serve as a shuttle/sink model to enhance cholesterol efflux and drug uptake in macrophage/foam cells.

Funder

National Natural Science Foundation of China

National Major Science and Technology Projects of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/C9TB02101A

Reference46 articles.

1. Atherosclerosis Is an Epigenetic Disease

2. Inflammation, Atherosclerosis, and Coronary Artery Disease

3. Macrophages in the Pathogenesis of Atherosclerosis

4. Progress and challenges in translating the biology of atherosclerosis

5. Atherosclerosis: current pathogenesis and therapeutic options

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