Synthesis of new alendronate analogs for bone-targeted drug delivery strategies-Reference-Cited by-同舟云学术

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Synthesis of new alendronate analogs for bone-targeted drug delivery strategies

Published:2024 Issue:3 Volume:48 Page:1436-1442
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Guedeney Nicolas¹^ORCID,Deschamp Julia¹^ORCID,Legigan Thibaut¹,Monteil Maëlle¹,Migianu-Griffoni Evelyne¹^ORCID,Lecouvey Marc¹

Affiliation:

1. Department of Chemistry, Université Sorbonne Paris Nord, UMR CNRS 7244; 1 rue de Chablis, F-93000 Bobigny, France

Abstract

1-Hydroxymethylene-1,1-bisphosphonate (HMBP) derivatives bearing a tunable side-chain function (azide, amine or maleimide) were developed to be used as bone vectors for imagery and bioactive compounds.

Funder

Centre National de la Recherche Scientifique

Ministère de l'Enseignement Supérieur et de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ04980A

Reference59 articles.

1. Bisphosphonate conjugation for bone specific drug targeting

2. Development of Bone Targeting Drugs

3. Diphosphonates Inhibit Hydroxyapatite Dissolution in vitro and Bone Resorption in Tissue Culture and in vivo

4. Targeted delivery to bone and mineral deposits using bisphosphonate ligands

5. Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

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