Evaluation of topologically distinct constrained antimicrobial peptides with broad-spectrum antimicrobial activity-Reference-Cited by-同舟云学术

Evaluation of topologically distinct constrained antimicrobial peptides with broad-spectrum antimicrobial activity

Published:2018 Issue:32 Volume:16 Page:5764-5770
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Yuan Fang¹²³⁴⁵^ORCID,Tian Yuan⁶⁷⁸³⁴,Qin Weirong⁴⁵⁹¹⁰¹¹,Li Jingxu⁴⁵⁹¹⁰¹¹,Yang Dan⁴⁵⁹¹⁰¹¹,Zhao Bingchuan⁴⁵⁹¹⁰¹¹,Yin Feng⁴⁵⁹¹⁰¹¹^ORCID,Li Zigang⁴⁵⁹¹⁰¹¹^ORCID

Affiliation:

1. Institute of Scientific and Technical Information of China

2. Beijing

3. China

4. The State Key Laboratory of Chemical Oncogenomics

5. School of Chemical Biology and Biotechnology

6. School of Life Science and Engineering

7. Southwest Jiaotong University

8. Chengdu

9. Peking University

10. Shenzhen Graduate School

11. Shenzhen

Abstract

Conformationally constrained peptides with either α-helical or β-hairpin conformations, possessing different topological distribution of hydrophobic and hydrophilic residues, displayed distinct anti-microbial activity towards Gram positive and Gram negative bacteria and fungi.

Funder

Peking University

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00483H

Reference83 articles.

1. Rapidly Rising Prevalence of Nosocomial Multidrug-Resistant, Gram-Negative Bacilli: A 9-Year Surveillance Study