Gradient scaffolds for osteochondral tissue engineering and regeneration

Author:

Zhang Bin1234ORCID,Huang Jie1234,Narayan Roger J.5678ORCID

Affiliation:

1. Department of Mechanical Engineering

2. University College London

3. London

4. UK

5. Joint Department of Biomedical Engineering

6. University of North Carolina and North Carolina State University

7. Raleigh

8. USA

Abstract

The tissue engineering approach for repairing osteochondral (OC) defects involves the fabrication of a biological tissue scaffold that mimics the physiological properties of natural OC tissue (e.g., the gradient transition between the cartilage surface and the subchondral bone).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference151 articles.

1. OARSI White Paper- OA as a Serious Disease ; Administration, F. a. D., World Health Organization, 2016

2. Repair of Articular Cartilage Defects: Review and Perspectives

3. L. M. Tibor and J. A.Weiss , Hip cartilage restoration: Overview , Hip Arthroscopy and Hip Joint Preservation Surgery , 2013 , pp. 1–19

4. The Treatment of Articular Cartilage Defects Using the Microfracture Technique

5. Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation

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