The development of small-molecule modulators for ClpP protease activity
Author:
Affiliation:
1. College of Life Sciences
2. Zhejiang Sci-Tech University
3. Hangzhou
4. China
5. Laboratory of Chemical Biology
6. State Key Laboratory of Drug Research
7. Shanghai Institute of Materia Medica
8. Chinese Academy of Sciences
9. Shanghai 201203
Abstract
Deregulating ClpP activity either through inhibition or overactivation could lead to antibacterial activity.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C6MB00644B
Reference85 articles.
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2. Targeting virulence: a new paradigm for antimicrobial therapy
3. Antibiotics for Emerging Pathogens
4. Bacterial proteolytic complexes as therapeutic targets
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