Is the H4 histone tail intrinsically disordered or intrinsically multifunctional?
Author:
Affiliation:
1. Yusuf Hamied Department of Chemistry
2. University of Cambridge
3. Cambridge
4. UK
Abstract
While the H4 histone tail exhibits a large structural variance associated with disorder, the energy landscape shows a high level of topographic order. This result opens a new perspective on how we interpret disorder.
Funder
Cambridge Philosophical Society
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CP/D0CP05405D
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5. Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions
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