Sustained release of heme–albumin as a potential novel therapeutic approach for age-related macular degeneration-Reference-Cited by-同舟云学术

Sustained release of heme–albumin as a potential novel therapeutic approach for age-related macular degeneration

Published:2022 Issue:24 Volume:10 Page:7004-7014
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Allyn Megan M.¹,Rincon-Benavides Maria A.²³,Chandler Heather L.⁴,Higuita-Castro Natalia²⁵,Palmer Andre F.¹,Swindle-Reilly Katelyn E.¹²⁶^ORCID

Affiliation:

1. William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 W Woodruff Ave, Columbus, OH 43210, USA

2. Department of Biomedical Engineering, The Ohio State University, 140 W 19th Ave, Columbus, OH 43210, USA

3. Biophysics Graduate Program, The Ohio State University, 484 W 12th Ave, Columbus, OH 43210, USA

4. College of Optometry, The Ohio State University, 338 W 10th Ave, Columbus, OH 43210, USA

5. Department of Surgery, The Ohio State University, 370 W 9th Ave, Columbus, OH 43210, USA

6. Department of Ophthalmology and Visual Sciences, The Ohio State University, 915 Olentangy River Rd, Columbus, OH 43212, USA

Abstract

ROS-responsive polydopamine nanoparticles sustain release of heme–albumin, increasing HO-1 expression in retinal cells, demonstrating a potential therapeutic approach for treatment of inflammatory conditions such as age-related macular degeneration.

Funder

Institute for Materials Research, Ohio State University

Ohio Lions Eye Research Foundation

College of Engineering, Ohio State University

Prevent Blindness Ohio

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00905F

Reference46 articles.

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