A novel calibration strategy for the quantitative imaging of iron in biological tissues by LA-ICP-MS using matrix-matched standards and internal standardisation

Author:

O'Reilly Jennifer12,Douglas David12,Braybrook Julian12,So P.-W.3456,Vergucht Eva789,Garrevoet Jan789,Vekemans Bart789,Vincze Laszlo789,Goenaga-Infante Heidi12

Affiliation:

1. LGC Ltd

2. Teddington, UK

3. Institute of Psychiatry

4. Department of Neuroimaging

5. King's College London

6. London, UK

7. Department of Analytical Chemistry

8. Ghent University

9. B-9000 Ghent, Belgium

Abstract

This paper describes the development of a simple and straightforward approach for preparation of matrix-matched calibration standards for Fe quantitative tissue imaging by LA-ICP-MS.

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

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