Closed-loop identification of enzyme kinetics applying model-based design of experiments-Reference-Cited by-同舟云学术

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Closed-loop identification of enzyme kinetics applying model-based design of experiments

Published:2024 Issue: Volume: Page:
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Hennecke Leon¹^ORCID,Schaare Lucas²,Skiborowski Mirko²^ORCID,Liese Andreas¹^ORCID

Affiliation:

1. Institute of Technical Biocatalysis, Hamburg University of Technology, Denickestr. 15, D-21073 Hamburg, Germany

2. Institute of Process Systems Engineering, Hamburg University of Technology, Schwarzenberg-Campus 4, D-21073 Hamburg, Germany

Abstract

This study presents an automated reactor platform for the identification of enzyme kinetic models using model-based design of experiments on the example of the reduction of NAD+ by formate dehydrogenase from Candida boidinii.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RE/D4RE00127C

Reference51 articles.

1. Role of Biocatalysis in Sustainable Chemistry

2. Biocatalysis

3. Embracing Nature’s Catalysts: A Viewpoint on the Future of Biocatalysis

4. Grand Challenges in Biocatalysis

5. High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution

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