A multifunctional molecular entity CuII–SnIV heterobimetallic complex as a potential cancer chemotherapeutic agent: DNA binding/cleavage, SOD mimetic, topoisomerase Iα inhibitory and in vitro cytotoxic activities-Reference-Cited by-同舟云学术

A multifunctional molecular entity CuII–SnIV heterobimetallic complex as a potential cancer chemotherapeutic agent: DNA binding/cleavage, SOD mimetic, topoisomerase Iα inhibitory and in vitro cytotoxic activities

Published:2015 Issue:59 Volume:5 Page:47439-47450
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tabassum Sartaj¹²³⁴,Asim Ahmad¹²³⁴,Khan Rais Ahmad¹⁵⁶⁷,Arjmand Farukh¹²³⁴,Rajakumar Dhivya⁸⁹¹⁰⁴,Balaji Perumalsamy⁸⁹¹⁰⁴,Akbarsha Mohammad Abdulkader¹¹⁹¹⁰⁴¹²

Affiliation:

1. Department of Chemistry

2. Aligarh Muslim University

3. Aligarh-202002

4. India

5. King Saud University

6. Riyadh

7. Kingdom of Saudi Arabia

8. Department of Biomedical Science

9. Bharathidasan University

10. Tiruchirappalli 620 024

11. Mahatma Gandhi-Doerenkamp Center (MGDC) for Alternatives to Use of Animals in Life Science Education

12. Department of Food Science and Nutrition

Abstract

New chiral l-valine-derived Schiff base complexes with the bioactive heterocyclic ligand scaffold pyrazole (Hpz) were designed and synthesized with a view to find their potential as anticancer chemotherapeutic drug candidates.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA07333B

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