The effect of structural configuration on the DNA binding and in vitro antioxidant properties of new copper(ii) N2O2 Schiff base complexes

Author:

Yusuf Tunde Lewis1ORCID,Akintayo Damilola Caleb2ORCID,Oladipo Segun Daniel3,Adeleke Adesola Abimbola3,Olofinsan Kolawole4,Vatsha Banele1,Mabuba Nonhlagabezo1

Affiliation:

1. Department of Chemical Sciences, University of Johannesburg, Doornfontein, P.O. BOX 17011, 2028 Johannesburg, South Africa

2. School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X54001, Durban, 4000, South Africa

3. Department of Chemical Sciences, Olabisi Onabanjo University, PMB 2002, Ago-Iwoye, Nigeria

4. Department of Biochemistry, Faculty of Natural and Applied Sciences, Nile University of Nigeria, Abuja, Nigeria

Abstract

DNA interaction with cis and trans-copper NO complexes favours the cis configuration due to low energies observed in the cis configuration.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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