Discovery and development of novel substituted monohydrazides as potent antifungal agents

Author:

Thamban Chandrika Nishad1,Green Keith D.1,Spencer Abbygail C.1,Tsodikov Oleg V.1ORCID,Garneau-Tsodikova Sylvie1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536-0596, USA

Abstract

Novel substituted monohydrazides synthesized for this study displayed broad-spectrum activity against various fungal strains, including a panel of clinically relevant Candida auris strains.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

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