Synthesis of nanostructured silica/hydroxyapatite hybrid particles containing amphiphilic triblock copolymer for effectively controlling hydration layer structures with cytocompatibility

Abstract

This is the first successful report to synthesize the nanostructured mesoporous silica (MS)/hydroxyapatite (HA) hybrid particles containing amphiphilic triblock copolymer. The controlled hydration layer structures on the hybrid particles significantly affected the protein secondary structures for providing the higher cytocompatibility.