Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies-Reference-Cited by-同舟云学术

Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies

Published:2015 Issue:129 Volume:5 Page:106448-106460
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mujahid M.¹²³,Yogeeswari P.⁴⁵⁶⁷³,Sriram D.⁴⁵⁶⁷³,Basavanag U. M. V.⁸⁹¹⁰¹¹,Díaz-Cervantes Erik⁸⁹¹⁰¹¹,Córdoba-Bahena Luis⁸⁹¹⁰¹¹,Robles Juvencio⁸⁹¹⁰¹¹,Gonnade R. G.¹²³,Karthikeyan M.¹²³,Vyas Renu¹²³,Muthukrishnan M.¹²³

Affiliation:

1. CSIR-National Chemical Laboratory

2. Pune

3. India

4. Medicinal Chemistry & Antimycobacterial Research Laboratory

5. Pharmacy Group

6. Birla Institute of Technology & Science – Pilani

7. Hyderabad 500 078

8. Departamento de Química y Departamento de Farmacia

9. Universidad de Guanajuato

10. Guanajuato

11. Mexico

Abstract

We report new spiro chromone scaffold derived molecules possessing in vitro anti-tubercular activities. QSAR based molecular modeling studies correlated the bioactivities with the frontier molecular orbital energies.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA21737G

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