Increasing small molecule drug developability in sub-optimal chemical space-Reference-Cited by-同舟云学术

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Increasing small molecule drug developability in sub-optimal chemical space

Published:2013 Issue:4 Volume:4 Page:673
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Ritchie Timothy J.,Macdonald Simon J. F.,Peace Simon,Pickett Stephen D.,Luscombe Christopher N.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2013/MD/C3MD00003F

Reference28 articles.

1. Time-Related Differences in the Physical Property Profiles of Oral Drugs

2. The influence of drug-like concepts on decision-making in medicinal chemistry

3. What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

4. Molecular obesity, potency and other addictions in drug discovery

5. Lead optimization in the nondrug-like space

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