Catalyst-free formation of 1,4-diketones by addition of silyl enolates to oxyallyl zwitterions in situ generated from α-haloketones-Reference-Cited by-同舟云学术

Catalyst-free formation of 1,4-diketones by addition of silyl enolates to oxyallyl zwitterions in situ generated from α-haloketones

Published:2015 Issue:83 Volume:5 Page:67901-67908
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Luo Juan¹²³⁴⁵,Jiang Qihua¹²³⁴⁵,Chen Hao¹²³⁴⁵,Tang Qiang¹²³⁴⁵

Affiliation:

1. Department of Medical Chemistry

2. College of Pharmacy

3. Chongqing Medical University

4. Chongqing 400016

5. P. R. China

Abstract

Here we report an efficient and practical method for the preparation of 1,4-diketones by direct coupling of α-haloketones with silyl enolates at room temperature. No catalysts were required in our protocol.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA12244A

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