Half sandwich Ru(ii)-acylthiourea complexes: DNA/HSA-binding, anti-migration and cell death in a human breast tumor cell line-Reference-Cited by-同舟云学术

Half sandwich Ru(ii)-acylthiourea complexes: DNA/HSA-binding, anti-migration and cell death in a human breast tumor cell line

Published:2017 Issue:38 Volume:46 Page:12865-12875
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Colina-Vegas Legna¹²³^ORCID,Luna-Dulcey Liany⁴²³,Plutín Ana M.⁵⁶⁷,Castellano Eduardo E.⁸⁹³,Cominetti Marcia R.⁴²³^ORCID,Batista Alzir A.¹²³

Affiliation:

1. Departamento de Química

2. Universidade Federal de São Carlos

3. Brasil

4. Departamento de Gerontologia

5. Departamento de Química Orgánica

6. Universidad de La Habana

7. Cuba

8. Instituto de Física de São Carlos

9. Universidade de São Paulo

Abstract

Eight Ru(ii) complexes were synthesized. The activities against MDA-MB-231 cells include anti-migration, arrest at the sub-G1 phase and cell death by apoptosis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/DT/C7DT01801K

Reference54 articles.

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5. In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

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