MRI-visible and pH-sensitive micelles loaded with doxorubicin for hepatoma treatment

Author:

Li Bo12345,Cai Mingyue12345,Lin Liteng12345,Sun Weitong6789,Zhou Zhimei12345,Wang Shiyin10111259,Wang Yong10111259ORCID,Zhu Kangshun12345,Shuai Xintao10111259ORCID

Affiliation:

1. Laboratory of Interventional Radiology

2. Department of Minimally Invasive Interventional Radiology

3. and Department of Radiology

4. the Second Affiliated Hospital of Guangzhou Medical University

5. Guangzhou

6. Pharmaceutical college of Jiamusi University

7. Jiamusi University

8. Jiamusi

9. China

10. PCFM Lab of Ministry of Education

11. School of Materials Science and Engineering

12. Sun Yat-sen University

Abstract

A novel pH-sensitive micelle was constructed to efficiently co-deliver SPIONs and doxorubicin for cancer theranostic application.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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5. M. E. Davis , Z.Chen and D. M.Shin , Nanoparticle therapeutics: an emerging treatment modality for cancer , in Nanoscience And Technology: A Collection of Reviews from Nature Journals , World Scientific , 2010 , pp. 239–250

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