Antimicrobial α-defensins as multi-target inhibitors against amyloid formation and microbial infection-Reference-Cited by-同舟云学术

Antimicrobial α-defensins as multi-target inhibitors against amyloid formation and microbial infection

Published:2021 Issue: Volume: Page:
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhang Yanxian¹²³,Liu Yonglan¹²³,Tang Yijing¹²³,Zhang Dong¹²³^ORCID,He Huacheng⁴⁵⁶^ORCID,Wu Jiang⁷⁸⁶,Zheng Jie¹²³^ORCID

Affiliation:

1. Department of Chemical, Biomolecular, and Corrosion Engineering

2. The University of Akron

3. USA

4. College of Chemistry and Materials Engineering

5. Wenzhou University

6. China

7. School of Pharmaceutical Sciences

8. Wenzhou Medical University

Abstract

We report a new “anti-amyloid and antimicrobial hypothesis” by discovering host-defense antimicrobial peptides of α-defensins containing β-sheet structures, which possess inhibition functions against amyloid aggregation and microbial infection.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC01133B

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