pH/redox dual-sensitive nanoparticles based on the PCL/PEG triblock copolymer for enhanced intracellular doxorubicin release

Author:

Cao Yan12345,Zhao Junqiang12345,Zhang Yumin67895,Liu Jianfeng67895,Liu Jinjian67895,Dong Anjie12345,Deng Liandong12345

Affiliation:

1. Department of Polymer Science and Technology and Key Laboratory of Systems Bioengineering of the Ministry of Education

2. School of Chemical Engineering and Technology

3. Tianjin University

4. Tianjin 300072

5. China

6. Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine

7. Institute of Radiation Medicine

8. Chinese Academy of Medical Science and Peking Union Medical College

9. Tianjin

Abstract

Acid/redox-dual sensitivities of nanoparticles based on PEG/PCL enhance the intracellular drug release of cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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