Integrating silicon/zinc dual elements with PLGA microspheres in calcium phosphate cement scaffolds synergistically enhances bone regeneration

Author:

Liang Weiwei12345,Gao Min1234,Lou Jingsheng6784,Bai Yunyang1234,Zhang Jing9101112,Lu Teliang9101112,Sun Xiaowen13234,Ye Jiandong9101112ORCID,Li Baowei6784,Sun Li6784,Heng Boon Chin14234,Zhang Xuehui1323415ORCID,Deng Xuliang123415

Affiliation:

1. Department of Geriatric Dentistry

2. Peking University School and Hospital of Stomatology

3. Beijing 100081

4. P. R. China

5. Department of Prosthodonitcs

6. Anesthesia and Operation Centre

7. Chinese PLA General Hospital

8. Beijing 410078

9. School of Materials Science and Engineering

10. South China University of Technology

11. Guangzhou 510641

12. China

13. Department of Dental Materials & Dental Medical Devices Testing Centre

14. Central Laboratory

15. National Engineering Laboratory for Digital and Material Technology of Stomatology

Abstract

Integrating multiple pro-osteogenic factors into bone graft substitutes is a practical and effective approach to improve bone repair efficacy.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Beijing Municipal Science and Technology Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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