Epigenetic modification of nucleic acids: from basic studies to medical applications

Author:

Chen Yuqi12345,Hong Tingting12345,Wang Shaoru12345,Mo Jing12345,Tian Tian12345,Zhou Xiang12345ORCID

Affiliation:

1. College of Chemistry and Molecular Sciences

2. Institute of Advanced Studies

3. Key Laboratory of Biomedical Polymers of Ministry of Education

4. Hubei Province Key Laboratory of Allergy and Immunology

5. Wuhan University

Abstract

This review focuses on the recent progresses in epigenetic modifications in DNA and RNA, including their epigenetic roles, detection methods and applications in clinical medicine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference214 articles.

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2. The RNA modification database, RNAMDB: 2011 update

3. R. H. Hall , The modified nucleosides in nucleic acids, Columbia University Press, New York, 1971

4. P. F. Agris , The Modified nucleosides of transfer RNA: a bibliography of biochemical and biophysical studies from 1970 to 1979, A. R. Liss, New York, 1980

5. Nucleic acid modifications with epigenetic significance

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