Total synthesis of [β-HIle]<sup>2</sup>-nodupetide: effect of ester to amide substitution on its antimicrobial activity-Reference-Cited by-同舟云学术

Total synthesis of [β-HIle]²-nodupetide: effect of ester to amide substitution on its antimicrobial activity

Published:2024 Issue:30 Volume:14 Page:21778-21785
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Farah Harra Ismi¹²,Supratman Unang¹³²^ORCID,Hidayat Ace Tatang¹³²,Maharani Rani¹³²^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Jatinangor, West Java, Indonesia

2. Pharmacy Faculty, Universitas Mulawarman, Samarinda 75242, East Kalimantan, Indonesia

3. Central Laboratory, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang KM 21, Jatinangor 45363, West Java, Indonesia

Abstract

[β-HIle]2-nodupetide is a nodupetide analogue, in which HMHA residue of nodupetide is replaced with β-HIle and it changes the ester to amide bond in the nodupetide's backbone.

Funder

Lembaga Pengelola Dana Pendidikan

Universitas Padjadjaran

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04401K

Reference25 articles.

1. Enhancing Chemical Stability through Structural Modification of Antimicrobial Peptides with Non-Proteinogenic Amino Acids

2. Nodupetide, a potent insecticide and antimicrobial from Nodulisporium sp. associated with Riptortus pedestris

3. Replacement of l-Amino Acids by d-Amino Acids in the Antimicrobial Peptide Ranalexin and Its Consequences for Antimicrobial Activity and Biodistribution

4. Impact of non-proteinogenic amino acids in the discovery and development of peptide therapeutics

5. A total synthesis of a highly N-methylated cyclodepsipeptide [2S,3S-Hmp]-aureobasidin L using solid-phase methods