Efficient skin interactions of graphene derivatives: challenge, opportunity or both?

Author:

Zabihi Fatemeh12,Tu Zhaoxu13ORCID,Kaessmeyer Sabine45ORCID,Schumacher Fabian6ORCID,Rancan Fiorenza2,Kleuser Burkhard6,Boettcher Christoph7,Ludwig Kai7,Plendl Johanna4,Hedtrich Sarah89,Vogt Annika2,Haag Rainer1ORCID

Affiliation:

1. Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, Berlin 14195, Germany

2. Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science, Charité Universitaetsmedizin Berlin, Germany

3. The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

4. Department of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, Germany

5. Division of Veterinary Anatomy, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland

6. Institute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, 14195 Berlin, Germany

7. Forschungszentrum für Elektronenmikroskopie, Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 36a, 14195 Berlin, Germany

8. Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, V6T1Z3 Vancouver, Canada

9. Berlin Institute of Health at Charité, Universitaetsmedizin Berlin, Lindenberger Weg 80, 13125 Berlin, Germany

Abstract

Positively and negatively charged graphene sheets interacted with human skin and enhanced penetration of Nile red-loaded into the epidermal and dermal layers of the skin. Moreover, graphene's cargo was released more efficiently into the skin layers after laser exposure.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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