A mechanically tough and ultra-swellable microneedle for acute gout arthritis-Reference-Cited by-同舟云学术

A mechanically tough and ultra-swellable microneedle for acute gout arthritis

Published:2023 Issue:5 Volume:11 Page:1714-1724
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Jiang Suping¹,Wang Wen¹,Ke Jiming¹,Huang Shan¹,Wang Jie¹,Luo Chengxi¹,Li Xiaoxia¹,Zhang Kaili¹,Liu Huanhuan¹²³⁴,Zheng Wensheng¹⁵,Zhang Jiwen¹⁶,Peng Can¹²⁷⁸

Affiliation:

1. School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, 230012, China

2. Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application, Heifei, Anhui, 230012, China

3. Engineering Technology Research Center of Modernized Pharmaceutics, Anhui Education Department (AUCM), Hefei 230012, China

4. Institute of Pharmaceutics, Anhui Academy of Chinese Medicine, Hefei 230012, China

5. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

6. Center for Drug Delivery System, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

7. Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, 230012, China

8. Institute of TCM Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, Anhui, 230012, China

Abstract

A tough and ultra-swellable microneedle was fabricated using in situ photopolymerization. Colchicine release was triggered by diffusion when microneedles were used on MSU-induced acute gout rats, resulting in decreased levels of inflammatory cytokines.

Funder

National Natural Science Foundation of China

Anhui Provincial Department of Education

National Science and Technology Major Project

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01937J

Reference48 articles.

1. Gout