Enzymatic approaches to site-selective oxidation of quinoline and derivatives

Author:

Wang Zhongqiang12,Zhao Ling12,Mou Xueqing12,Chen Yongzheng12ORCID

Affiliation:

1. Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, 563000 Zunyi, People's Republic of China

2. Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, 563000 Zunyi, People's Republic of China

Abstract

This review collates examples of the use of biological methods to oxidize the pyridine portion of quinoline and its structural analogues 1,2,3,4-tetrahydroquinoline, isoquinoline and 1,2,3,4-tetrahydroisoquinoline.

Funder

National Natural Science Foundation of China

Guizhou Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference108 articles.

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2. Progress in the Chemistry of Tetrahydroquinolines

3. G.Diaz , I. L.Miranda and M. A. N.Diaz , Quinolines, Isoquinolines, Angustureine, and Congeneric Alkaloids-Occurrence, Chemistry, and Biological Activity , in Phytochemicals: Isolation, Characterisation and Role in Human Health , ed. A. V. Rao and L. G. Rao , InTech, Janeza Trdine 9 , 51000 Rijeka, Croatia , 2015 , ch. 6, pp. 141–162

4. Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

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