Syntheses of 12H-benzo[a]xanthen-12-ones and benzo[a]acridin-12(7H)-ones through Au(i)-catalyzed Michael addition/6-endo-trig cyclization/aromatization cascade annulation

Author:

Xiong Zhiling12345,Zhang Xinhang12345,Li Yangming12345,Peng Xiaoshi12345,Fu Jiayue12345,Guo Jiajia12345,Xie Fukai12345,Jiang Chongguo12345,Lin Bin12345,Liu Yongxiang12345ORCID,Cheng Maosheng12345

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

2. Ministry of Education

3. Shenyang 110016

4. P. R. China

5. Institute of Drug Research in Medicine Capital of China

Abstract

A gold(i)-catalyzed cascade strategy to synthesize both 12H-benzo[a]xanthen-12-ones and benzo[a]acridin-12(7H)-ones was developed.

Funder

National Natural Science Foundation of China

Foundation of Liaoning Province Education Administration

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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