Aglycone mimics for tuning of glycosidase inhibition: design, synthesis and biological evaluation of bicyclic pyrrolidotriazole iminosugars-Reference-Cited by-同舟云学术

Aglycone mimics for tuning of glycosidase inhibition: design, synthesis and biological evaluation of bicyclic pyrrolidotriazole iminosugars

Published:2016 Issue:16 Volume:6 Page:13014-13026
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Arora Inderpreet¹²³⁴,Sharma Sandeep K.⁵²³⁴,Shaw Arun K.¹²³⁴

Affiliation:

1. Division of Medicinal and Process Chemistry

2. CSIR-Central Drug Research Institute

3. Lucknow 226031

4. India

5. Microbiology Division

Abstract

Various fuco-configured bicyclic pyrrolidotriazole aglycone mimics were synthesised using copper-catalysed coupling of allyl bromides with terminal alkynes and Sonogashira–Hagihara reaction followed by intramolecular azide-alkyne ‘click’ reaction.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA26005A

Reference79 articles.

1. Nitrogen-in-the-Ring Pyranoses and Furanoses: Structural Basis of Inhibition of Mammalian Glycosidases

2. P. Compain and O. R.Martin, Iminosugars: From Synthesis to Therapeutics Applications, John Wiley, Chichester, 2007

3. Covalent inhibitors of glycosidases and their applications in biochemistry and biology

4. Nomenclature of carbohydrates (IUPAC Recommendations 1996)

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