Selective divergent radical cyclization of 1,6-dienes with alkyl nitriles

Author:

Kang Qing-Qing1,Liu Yi1,Wu Shi-Ping1,Ge Guo-Ping1,Zheng Hongxing2,Zhang Jun-Qi3,Wei Wen-Ting1ORCID

Affiliation:

1. Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang, 315211, China

2. Institution of Functional Organic Molecules and Materials, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong, 252059, China

3. Advanced Research Institute and Department of Chemistry, Taizhou University, 1139 Shifu Avenue, Taizhou, 318000, China

Abstract

An efficient, selective, and step economical radical cyclization of 1,6-dienes with alkyl nitriles initiated by α-C(sp3)–H functionalization under the Sc(OTf)3 and Ag2CO3 system is described here.

Funder

Natural Science Foundation of Hunan Province

Zhejiang University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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