DNA-protamine condensates under low salt conditions: molecular dynamics simulation with a simple coarse-grained model focusing on electrostatic interactions

Author:

Jang Yun Hee123ORCID,Raspaud Eric3,Lansac Yves123ORCID

Affiliation:

1. GREMAN UMR 7347, Université de Tours, CNRS, INSA CVL, 37200 Tours, France

2. Department of Energy Science and Engineering, DGIST, Daegu 42988, Korea

3. Laboratoire de Physique des Solides, CNRS UMR 8502, Université Paris-Saclay, 91405 Orsay, France

Abstract

Simple coarse-grained model with long-range electrostatic interactions providing a nanoscale picture of DNA aggregation–redissolution behaviours controlled by protamine-DNA charge ratios and protamine length in low-salt regime.

Funder

National Research Foundation of Korea

Korea Institute of Science and Technology Information

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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