Development of magnetic nanoparticles with double silica shells of different porosities for efficient siRNA delivery to breast cancer cells-Reference-Cited by-同舟云学术

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Development of magnetic nanoparticles with double silica shells of different porosities for efficient siRNA delivery to breast cancer cells

Published:2024 Issue:4 Volume:5 Page:1626-1630
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Bao Qing¹,Liu Xiangyu¹,Li Yan²^ORCID,Yang Tao¹,Yue Hui¹,Yang Mingying²^ORCID,Mao Chuanbin³^ORCID

Affiliation:

1. School of Materials Science and Engineering, Zhejiang University, 310058, China

2. College of Animal Science, Zhejiang University, 310058, China

3. Department of Biomedical Engineering, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China

Abstract

Silica-based magnetic nanoparticles are designed to deliver siRNA to triple negative breast cancer cells. The cells are killed due to siRNA-induced apoptosis upon the magnetic field-enhanced efficient cellular uptake and endosome escape of siRNA.

Funder

National Natural Science Foundation of China

Science and Technology Program of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MA/D3MA00568B

Reference20 articles.

1. RNA-based diagnostic and therapeutic strategies for cardiovascular disease

2. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility

3. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics

4. Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles

5. Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-like Mechanism of Action

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