Simultaneous control of the mechanical properties and adhesion of human umbilical vein endothelial cells to suppress platelet adhesion on a supramolecular substrate

Author:

Park Junsu12ORCID,Ueda Tomoya3ORCID,Kawai Yusaku1ORCID,Araki Kumiko3,Kido Makiko1,Kure Bunsho4,Takenaka Naomi4,Takashima Yoshinori1526ORCID,Tanaka Masaru3ORCID

Affiliation:

1. Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan

2. Forefront Research Center, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan

3. Institute for Materials Chemistry and Engineering, Kyushu University, CE41 744 Motooka, Nishi, Fukuoka 819-0395, Japan

4. Nara Laboratory, Kyoeisha Chemical Co., Ltd, 2-5,5-chome, Saikujo-cho, Nara 630-8453, Japan

5. Institute for Advanced Co-Creation Studies, Osaka University, 1-1 Yamadaoka, Suita, Osaka 565-0871, Japan

6. Innovative Catalysis Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 1-1 Yamadaoka, Suita, Osaka 565-0871, Japan

Abstract

Supramolecular cross-links in poly(2-methoxyethyl acrylate) enhanced mechanical properties of the polymers maintaining high blood compatibility. The high blood compatibility suggests a potential for artificial blood vessel.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Kao Foundation for Arts and Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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