Computer-aided structure-based optimization of 4,5,6,7-tetrahydrobenzo[<i>d</i>]thiazole-2,6-diamine derivatives as DNA gyrase B inhibitors-Reference-Cited by-同舟云学术

Computer-aided structure-based optimization of 4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine derivatives as DNA gyrase B inhibitors

Published:2023 Issue:8 Volume:47 Page:3692-3702
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Gutierrez Lucas J.¹²,Vettorazzi Marcela¹³,Dernovšek Jaka⁴^ORCID,Durcik Martina⁴,Mašič Lucija Peterlin⁴,Tomašič Tihomir⁴^ORCID,Enriz Ricardo D.¹²^ORCID

Affiliation:

1. Universidad Nacional de San Luis, Facultad de Química, Bioquímica y Farmacia, Ejército de los Andes 950, 5700, San Luis, Argentina

2. IMIBIO-CONICET, UNSL, Ejército de los Andes 950, 5700, San Luis, Argentina

3. IMASL-CONICET, UNSL, Ejército de los Andes 950, 5700, San Luis, Argentina

4. University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Aškerčeva cesta 7, 1000, Ljubljana, Slovenia

Abstract

Here we report a theoretical-experimental study of 4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine derivatives that act as inhibitors of bacterial DNA gyrase B (GyrB).

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Fondo para la Investigación Científica y Tecnológica

Javna Agencija za Raziskovalno Dejavnost RS

Universidad Nacional de San Luis

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D2NJ05103F

Reference43 articles.